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Updated: Oct 11, 2025

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
Published on: March 3, 2020
In-syringe dispersive liquid-liquid microextraction
Valfredo Azevedo Lemos1, Jeferson Alves Barreto2, Luana Bastos Santos1
1Universidade Estadual do Sudoeste da Bahia, Laboratório de Química Analítica, Campus de Jequié, 45208-091, Jequié, Bahia, Brazil; Universidade Federal da Bahia, Programa de Pós-Graduação em Química, Campus Universitário de Ondina, 40170-280, Salvador, Bahia, Brazil.
Abstract:
Dispersive liquid-liquid microextraction (DLLME) has recently been widely used in the separation and preconcentration of various chemical species. Among the various approaches using DLLME are systems that use a syringe as an extraction environment. In this review, details of some methods that use this approach are presented. The ways to promote dispersion, analytical characteristics, and the advantages and disadvantages of the methods, among other aspects, are discussed critically. Finally, some trends in the use of in-syringe microextraction systems are described.

