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Case report of primary CD20 negative diffuse large B-cell lymphoma.
Kanti Devi1, Natashi Ali2, Arsalan Ahmed2
1Department of Medical Oncology, Aga Khan University, Karachi, Pakistan.
Oxford Medical Case Reports
|December 3, 2021
Summary
This case report details a rare instance of CD20 negative diffuse large B cell lymphoma (DLBCL), an aggressive non-Hodgkin
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Aggressive non-Hodgkin's lymphomas (NHL) that are refractory to standard chemotherapy are rare.
- Primary CD20 negative diffuse large B cell lymphoma (DLBCL) is an uncommon presentation, particularly without HIV infection.
Observation:
- A case of primary CD20 negative DLBCL was observed.
- The patient did not have a human immunodeficiency virus infection.
- This presentation posed diagnostic and therapeutic challenges.
Findings:
- The study highlights the rarity of CD20 negative DLBCL.
- It underscores the diagnostic and treatment complexities associated with this NHL subtype.
Implications:
- This case may inform diagnostic and treatment strategies for rare aggressive lymphomas.
- Further research into CD20 negative DLBCL is warranted.
- Understanding uncommon lymphoma presentations is crucial for improving patient outcomes.
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