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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Introduction Cardiac Emergencies01:30

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Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Snake Bite and Dengue: A Twin Tragedy.

Satish Mahajan1, Akhilesh Annadatha1, Dhruv Talwar1

  • 1Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Science (Deemed to be University), Wardha, IND.

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Summary

This case report details a patient with a concurrent Dengue and snakebite infection. Managing this dual diagnosis presented unique challenges in patient care.

Keywords:
dengue feverneuroparalytic snake bitesnake bitetropical diseaseviral infection

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Area of Science:

  • Arbovirology
  • Toxicology
  • Infectious Diseases

Background:

  • Dengue fever, a viral infection transmitted by Aedes mosquitoes, causes severe myalgia ('Break Bone fever').
  • Snakebite envenomation is a significant global health issue, particularly in tropical agricultural regions, with varied clinical presentations from mild to life-threatening.
  • Potential complications of snakebite include respiratory paralysis, coagulopathy, and rhabdomyolysis leading to acute kidney injury.

Observation:

  • A patient presented with a snakebite envenomation.
  • The patient was concurrently diagnosed with Dengue virus infection.

Findings:

  • The co-occurrence of Dengue and snakebite complicated the clinical management of the patient.
  • This case highlights the diagnostic and therapeutic challenges posed by dual infections.

Implications:

  • Concurrent Dengue and snakebite infections require careful consideration for effective patient management.
  • Understanding the interplay between these conditions is crucial for improving clinical outcomes.
  • This case underscores the importance of considering co-infections in endemic areas.