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Ventricular enlargement in young chronic schizophrenics
Acta Psychiatrica Scandinavica
|January 1, 1986
Summary
Schizophrenia patients show enlarged lateral ventricles, a key brain structure. This study found no link between ventricular brain ratio and patient age or illness duration.
Area of Science:
- Neuroscience
- Psychiatry
- Radiology
Background:
- Schizophrenia is a complex mental disorder.
- Brain imaging studies have investigated structural abnormalities in schizophrenia.
- The ventricular brain ratio (VBR) is a measure used to assess brain structure.
Purpose of the Study:
- To investigate the ventricular brain ratio (VBR) in young, in-patient schizophrenic individuals.
- To determine if VBR is associated with age or the duration of illness in schizophrenia patients.
Main Methods:
- A case-control study design was employed.
- The ventricular brain ratio (VBR) was measured using neuroimaging techniques.
- Participants included 33 young in-patient schizophrenics and 25 healthy controls.
Main Results:
- Significant lateral ventricular enlargement was confirmed in schizophrenic patients compared to controls.
- No statistically significant association was found between VBR and age.
- No statistically significant association was found between VBR and the length of illness.
Conclusions:
- Lateral ventricular enlargement is a characteristic finding in this sample of young schizophrenic patients.
- VBR in this group is not influenced by age or duration of illness.
- Further research is needed to explore other factors influencing VBR in schizophrenia.