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Updated: Oct 11, 2025

The MultiBac Protein Complex Production Platform at the EMBL
Published on: July 11, 2013
How multi-component cascades operate in cells: lessons from the ubiquitin system-containing liquid-separated
Afu Fu1, Ido Livneh1, Aaron Ciechanover1
1The Rappaport Technion Integrated Cancer Center, the Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa, Israel.
Abstract:
Membraneless condensates have recently caught the attention of biologists as hubs for cellular components required for catalysis of basic processes. Whether they are real has become the center of heated discussion where the main issues are their mechanism of assembly and function. A recent study describing these condensates as hubs for protein degradation by the ubiquitin system may shed a new light on this recent development in cell biology.
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