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Sudden hearing loss associated with piroxicam.
The American Journal of Otology
|March 1, 1986
Summary
Piroxicam, a nonsteroidal anti-inflammatory drug, may cause permanent hearing loss and tinnitus. While temporary cases are known, this is the first reported instance of permanent damage from the drug.
Area of Science:
- Otolaryngology
- Pharmacology
- Toxicology
Background:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for pain and inflammation.
- Piroxicam (Feldene) is an NSAID associated with various side effects.
- Previous reports have linked piroxicam use to tinnitus and temporary hearing loss.
Observation:
- A patient developed permanent hearing loss and tinnitus.
- The patient's symptoms were associated with the use of piroxicam.
Findings:
- This case represents the first documented instance of permanent hearing loss and tinnitus linked to piroxicam use.
- The findings suggest a potential for irreversible ototoxicity with piroxicam.
Implications:
- Clinicians should be aware of the risk of permanent hearing damage with piroxicam.
- Further research into the ototoxic mechanisms of piroxicam is warranted.
- Patients experiencing auditory symptoms while on piroxicam should seek medical evaluation.