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Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...
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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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Pharmacy technicians recognize medication packaging problems but rarely discuss them with patients. Integrating packaging guidance into drug dispensing counseling is crucial for patient safety and adherence.

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Area of Science:

  • Pharmaceutical Sciences
  • Patient Safety
  • Health Services Research

Background:

  • Pharmacy technicians are well-positioned to discuss medication use with patients.
  • Current practices lack systematic patient education on medication packaging.
  • Unclear if technicians proactively address packaging challenges.

Purpose of the Study:

  • Assess pharmacy technicians' identification of medication packaging problems.
  • Determine how technicians assist patients with packaging issues.
  • Explore solutions for packaging-related difficulties.

Main Methods:

  • Cross-sectional study design.
  • Semistructured interviews with 31 pharmacy technicians across 31 pharmacies.
  • Assessment of packaging difficulties and proposed solutions.

Main Results:

  • All technicians acknowledge packaging problems, though patients seldom report them.
  • Technicians can find solutions but often only after patient-initiated problems.
  • Suggested solutions include counseling, packaging modification, and assistive tools.

Conclusions:

  • Pharmacy technicians are aware of and can solve packaging issues.
  • Systematic attention to medication packaging during dispensing is lacking.
  • Standardizing packaging discussions in counseling and developing support procedures are recommended.