Related Experiment Video
Updated: Oct 11, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
A Case of Thyroid Storm Induced by Iodine-Containing Dietary Supplements and Homeopathic Remedies
Katie Karkowski1, James L Carroll2
1University of Rhode Island, Kingston, RI, USA.
Abstract:
Objective: We report the case of a patient who presented to the hospital in thyroid storm following the use of several iodine-containing dietary supplements (DS) and homeopathic remedies (HR). Case Summary: The patient was a 76-year-old woman with no personal or family history of thyroid or autoimmune disease. On laboratory assessment, a thyroid panel showed that her total T3 and T4 were elevated at 334 ng/dL and 14.6 µg/dL, respectively; thyroid stimulating hormone was undetectable; and thyroid stimulating immunoglobulin was positive at 7.4. The patient had been consuming 170 µg of iodine daily for the past 2 months via her DS and HR. An objective causality assessment using the Naranjo adverse drug reaction probability scale revealed that an adverse effect was probable. The patient likely suffered from iodine-induced thyrotoxicosis secondary to the consumption of numerous DS and HR. Discussion: Dietary supplements and homeopathic remedies can pose significant health risks. The safety of these products is not assured as they are incompletely monitored by the Food and Drug Administration. Individuals who take these compounds do so at their own risk and should pay close attention to product contents. Conclusions: The labeling of DS and HR products may be misleading. Pharmacists and clinicians are advised to inquire about the use of DS and HR products. When use is identified, the products should be subject to a thorough review.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Homeostatic Imbalances in Body Temperature
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...

