Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

2.9K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
2.9K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.9K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.9K
iPS Cell Differentiation01:22

iPS Cell Differentiation

2.8K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interdisciplinary consensus statements on imaging of scaphoid fractures.

European radiology·2026
Same author

Interdisciplinary consensus statements on imaging of DRUJ instability and TFCC injuries.

European radiology·2023
Same author

Wrist Trauma: More Than Bones.

Journal of the Belgian Society of Radiology·2022
Same author

Arthroscopically Assisted Eaton-Littler Trapeziometacarpal Ligamentoplasty.

Journal of wrist surgery·2021
Same author

Volar Ganglion Cyst and Echo-Guided Assistance for the Arthroscopic Removal.

Hand clinics·2021
Same author

Use of Sonography in Hand/Upper-Extremity Surgery: Innovative Concepts and Techniques.

Hand clinics·2021

Related Experiment Video

Updated: Oct 11, 2025

Optimized Workflow for Iterative Bleaching Extends Multiplexity Imaging of Highly Autofluorescent Clinical Samples
06:52

Optimized Workflow for Iterative Bleaching Extends Multiplexity Imaging of Highly Autofluorescent Clinical Samples

Published on: July 11, 2025

343

Kienböck's disease in 2021.

Emmanuel J Camus1, Luc Van Overstraeten2

  • 1IMPPACT, Clinique de Lille Sud, 96, rue Gustave Delory, 59810 Lesquin, France; IMPPACT, Clinique du Val de Sambre, 162, route de Mons, 59600 Maubeuge, France; IMPPACT, Clinique du Cambrésis, 102, Bd Faidherbe, 59400 Cambrai, France; ULB Laboratoire d'anatomie fonctionnelle, 808, route de Lennik, 1070 Brussels, Belgium.

Orthopaedics & Traumatology, Surgery & Research : OTSR
|December 3, 2021
PubMed
Summary

Kienböck's disease, a condition affecting the lunate bone, is likely caused by inflammation and thrombosis. Surgical decompression osteotomies protect the lunate from collapse, potentially allowing biological healing.

Keywords:
CamembertHistoryKienböck's diseaseOsteotomyTreatment

More Related Videos

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

4.8K
A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
13:34

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

Published on: April 6, 2016

10.3K

Related Experiment Videos

Last Updated: Oct 11, 2025

Optimized Workflow for Iterative Bleaching Extends Multiplexity Imaging of Highly Autofluorescent Clinical Samples
06:52

Optimized Workflow for Iterative Bleaching Extends Multiplexity Imaging of Highly Autofluorescent Clinical Samples

Published on: July 11, 2025

343
TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
09:00

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

4.8K
A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
13:34

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

Published on: April 6, 2016

10.3K

Area of Science:

  • Orthopedics
  • Hand Surgery
  • Radiology

Background:

  • Kienböck's disease, characterized by avascular necrosis of the lunate, has an unclear etiology.
  • Progression often leads to wrist degeneration, with conservative treatments yielding poor results in adults.
  • Surgical intervention is frequently necessary due to the limitations of non-operative management.

Purpose of the Study:

  • To explore the underlying causes and pathophysiology of Kienböck's disease.
  • To evaluate the effectiveness of various surgical decompression osteotomy techniques.
  • To compare the biomechanical effects of different surgical approaches on the lunate bone.

Main Methods:

  • Review of existing literature on Kienböck's disease and surgical treatments.
  • Analysis of anatomical factors and their contribution to lunate pathology.
  • Comparison of biomechanical outcomes for different osteotomy procedures.

Main Results:

  • Kienböck's disease may stem from inflammatory, biological venous thrombosis leading to intraosseous compartment syndrome.
  • Certain anatomical factors may predispose to fracture rather than necrosis.
  • Decompression osteotomies protect the lunate from collapse but do not heal the necrosis itself.

Conclusions:

  • While the exact cause of Kienböck's disease remains elusive, surgical decompression is crucial for preventing lunate collapse.
  • Extra-articular techniques preserving vascularization and mid-carpal anatomy are advantageous.
  • Further research into biological treatments is warranted, though current palliative options address advanced degeneration.