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Updated: Oct 11, 2025

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Isolation of Mouse Interstitial Valve Cells to Study the Calcification of the Aortic Valve In Vitro
Published on: May 10, 2021
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Calcification Causing Failure of Tissue Engineered Bovine Pericardium After Aortic Valve Repair
Aditya A Patukale1,2,3, Janene Davies4, Supreet Marathe1,2,3
1Queensland Paediatric Cardiac Service, 67568Queensland Children's Hospital, Brisbane, Australia.
World Journal for Pediatric & Congenital Heart Surgery
|December 4, 2021
Abstract:
CardioCel® is bovine pericardium which is subjected to a novel tissue engineering process (ADAPT®) to reduce cytotoxicity and retard calcification while maintaining strength and elasticity. We present a case where CardioCel® showed rapid degeneration and calcification after repair of an aortic valve.

