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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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The CHA2DS2-VASc risk score predicts successful endovascular treatment in patients with acute ischemic stroke

Erdoğan Yaşar1, Yahya Akalın2, İbrahim Aktaş1

  • 1Department of Cardiology, Malatya Training and Research Hospital, Malatya, Turkey.

Acta Neurologica Scandinavica
|December 4, 2021
PubMed

Insights

The CHA2DS2-VASC score predicts endovascular intervention success in acute ischemic stroke patients. Higher scores indicate a greater risk of unsuccessful treatment, aiding in risk stratification for stroke patients.

Area of Science:

  • Neurology
  • Cardiology
  • Interventional Radiology

Background:

  • Acute ischemic stroke is a leading cause of death and disability globally.
  • Percutaneous endovascular intervention is a critical treatment for ischemic stroke, with success directly impacting patient outcomes.
  • The CHA2DS2-VASC score is a validated tool for assessing stroke risk in patients with atrial fibrillation.

Purpose of the Study:

  • To investigate the association between the CHA2DS2-VASC score and the success of endovascular intervention in acute ischemic stroke patients.
  • To determine if the CHA2DS2-VASC score can predict intervention failure.

Main Methods:

  • A retrospective analysis of 102 patients with acute ischemic stroke undergoing endovascular intervention.
  • Recording of admission CHA2DS2-VASC scores for all participants.
  • Evaluation of the correlation between TICI scores (indicating intervention success) and CHA2DS2-VASC scores post-procedure.

Main Results:

  • Patients with unsuccessful interventions had significantly higher CHA2DS2-VASC scores (5.02 ± 1.77) compared to those with successful interventions (2.78 ± 1.44).
  • A CHA2DS2-VASC score ≥3 was identified as a predictor of unsuccessful intervention (76.6% sensitivity, 83.3% specificity, AUC 0.827).
  • Atrial fibrillation and higher CHA2DS2-VASC scores were independent predictors of intervention failure in multivariate analysis.

Conclusions:

  • The CHA2DS2-VASC score is significantly associated with the success of endovascular interventions in acute ischemic stroke.
  • This score can serve as a valuable tool for predicting intervention outcomes and guiding clinical decision-making.
  • Risk stratification using the CHA2DS2-VASC score may help optimize treatment strategies for stroke patients.
Abstract

Keywords:
CHA2DS2-VASc scoreacute ischemic strokeendovascular treatment

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