Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Preparation of Samples for Electron Microscopy

Preparation of Samples for Electron Microscopy

To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A case report of spherical pneumonia caused by <i>Chlamydia psittaci</i> infection.

Frontiers in medicine·2026

Same author

Optimized Pretreatment for Raman-Based Nanoplastics Detection.

Analytical chemistry·2026

Same author

Artificial Raman Expert: Autonomous Spectroscopic Reasoning Driven by Localized Large Language Models.

ACS sensors·2026

Same author

Biocompatible, Tunable, Multifunctional Adhesive Silk-PDA Composite Films for Modern Labeling Needs.

ACS applied materials & interfaces·2026

Same author

Nanomechanical Gravimetric Analysis of Single Microdroplets for Liquid Biopsy.

ACS sensors·2026

Same author

Machine-Learning Microfluidic Minute-Scale Microorganism Metrics Monitoring(M6).

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Search research articles

Related Experiment Video

Updated: Jun 27, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

Sorting Gold and Sand (Silica) Using Atomic Force Microscope-Based Dielectrophoresis.

Chungman Kim^1,2, Sunghoon Hong¹, Dongha Shin^1,3

¹Department of Physics and Astronomy, Seoul National University, Seoul, 08826, Republic of Korea.

Nano-Micro Letters

|December 4, 2021

Summary

This study introduces a novel dielectrophoresis (DEP) technique for 3D printing, enabling selective sorting and deposition of multiple materials from a single nozzle. This advancement enhances multi-material fabrication capabilities.

Keywords:

Additive 3D printing Dielectrophoresis-empowered Pipette/AFM platform Multimaterial nano-patterning Nanopipette-based atomic force microscope On-demand materials sorting

More Related Videos

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight

Published on: October 11, 2016

Preparation of Janus Particles and Alternating Current Electrokinetic Measurements with a Rapidly Fabricated Indium Tin Oxide Electrode Array

Preparation of Janus Particles and Alternating Current Electrokinetic Measurements with a Rapidly Fabricated Indium Tin Oxide Electrode Array

Published on: June 23, 2017

Related Experiment Videos

Last Updated: Jun 27, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis

Published on: September 3, 2013

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight

Published on: October 11, 2016

Preparation of Janus Particles and Alternating Current Electrokinetic Measurements with a Rapidly Fabricated Indium Tin Oxide Electrode Array

Preparation of Janus Particles and Alternating Current Electrokinetic Measurements with a Rapidly Fabricated Indium Tin Oxide Electrode Array

Published on: June 23, 2017

Area of Science:

Materials Science
Nanotechnology
Engineering

Background:

Additive manufacturing (3D printing) excels at creating complex structures but struggles with simultaneous multi-material deposition.
Current methods lack efficient ways to sort and deposit diverse materials from a single reservoir through one nozzle.

Purpose of the Study:

To develop and demonstrate a dielectrophoresis (DEP)-based technique for selective material deposition and sorting.
To enable multi-material printing capabilities using a single nozzle.

Main Methods:

Utilized a pipette-based quartz tuning fork (QTF)-atomic force microscope (AFM) platform integrated with dielectrophoresis (DEP).
Demonstrated multi-material sorting of gold (Au) and silica nanoparticles in ambient conditions.
Validated spatial separation accuracy using surface-enhanced Raman spectroscopy (SERS) and computational simulations.

Main Results:

Achieved 95% accuracy in the spatial separation of different nanoparticles.
Confirmed successful multi-material sorting and deposition through a single nozzle.
Experimental results showed qualitative agreement with system simulations.

Conclusions:

The proposed DEP-based technique, DEPQA, effectively enables selective deposition and sorting of multiple materials.
This method significantly expands the potential of 3D printing for multi-material patterning and nano-micro fabrication.
The integration of DEP, AFM, and SERS opens avenues for advanced applications in materials science and engineering.