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[Cerebral venous thrombosis revealing neurosyphilis]

O Chol1, S Gallet2, L Bouillet1

  • 1Service de médecine interne, CHU de Grenoble Alpes, CS10217, 38043 Grenoble cedex 09, France.

La Revue De Medecine Interne
|December 5, 2021
PubMed
Abstract

Insights

Neurosyphilis, a rare syphilis complication, can cause cerebral venous thrombosis. Early diagnosis and penicillin treatment led to a favorable outcome in a recent case, highlighting syphilis as a potential cause of neurological disorders.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • Syphilis is a growing bacterial infection concern in France.
  • Neurosyphilis, a rare manifestation, affects meninges and blood vessels, rarely causing stroke.
  • Syphilitic venous thrombosis is an infrequently documented condition.

Observation:

  • A 50-year-old presented with decreased vision and headache.
  • Imaging revealed cerebral venous thrombosis; lumbar puncture indicated neurosyphilis.
  • The patient experienced bilateral papilledema.

Findings:

  • Cerebral venous thrombosis associated with neurosyphilis is poorly described.
  • This case highlights syphilis as a 'great simulator' in neurology.
  • Treatment involved penicillin G and anticoagulation.

Implications:

  • Neurosyphilis should be considered in unexplained neurological disorders.
  • The worldwide resurgence of syphilis necessitates increased clinical suspicion.
  • Prompt diagnosis and treatment of neurosyphilis are crucial for favorable outcomes.
Keywords:
Cerebral venous thrombosisLymphocytic meningitisMéningite lymphocytaireNeurosyphilisThrombose veineuse cérébrale

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