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Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

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IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Related Experiment Video

Updated: Oct 11, 2025

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
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Breast imaging: Beyond the detection.

Francesca Galati1, Giuliana Moffa1, Federica Pediconi1

  • 1Department of Radiological, Oncological and Pathological Sciences, "Sapienza" - University of Rome, Viale Regina Elena, 324, 00161 Rome, Italy.

European Journal of Radiology
|December 5, 2021
PubMed
Summary

Breast cancer imaging advances aim to noninvasively predict subtypes. Radiogenomics links imaging features with tumor molecular and genomic data for better treatment outcomes.

Keywords:
Artificial intelligenceAutomated breast ultrasoundContrast-enhanced mammographyDigital breast tomosynthesisMagnetic resonance imagingRadionuclide breast imaging

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Area of Science:

  • Oncology
  • Radiology
  • Genomics

Background:

  • Breast cancer is a complex disease with diverse subtypes requiring tailored treatments.
  • Effective treatment and survival depend on understanding tumor heterogeneity.
  • Noninvasive methods to predict these differences are crucial for personalized medicine.

Purpose of the Study:

  • To review current breast imaging techniques for predicting breast cancer subtypes.
  • To explore the role of quantitative imaging biomarkers and radiogenomics.
  • To discuss technological innovations in breast cancer diagnostics.

Main Methods:

  • Review of current breast imaging modalities (e.g., mammography, ultrasound, MRI).
  • Analysis of multiparametric studies combining qualitative and quantitative imaging parameters.
  • Exploration of radiogenomics, linking imaging to molecular and genomic tumor features.

Main Results:

  • Breast imaging can noninvasively assess tumor characteristics and predict subtypes.
  • Quantitative imaging biomarkers offer insights into clinical-pathological features.
  • Radiogenomics reveals correlations between imaging phenotypes and tumor genomics.

Conclusions:

  • Advanced breast imaging techniques are vital for noninvasive prediction of breast cancer heterogeneity.
  • Multiparametric analysis and radiogenomics enhance diagnostic capabilities.
  • Technological innovations in imaging are improving treatment strategies and patient outcomes.