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The Impact of the COVID-19 Pandemic on Corneal Transplantation in Brazil
Aline Silveira Moriyama1,2, João Luís Erbs Pessoa3, Taciana Ribeiro Silva Bessa4
1Hospital Oftalmológico de Sorocaba/Banco de Olhos de Sorocaba (Sorocaba Eye Hospital/ Sorocaba Eye Bank), Sorocaba, Brazil.
Insights
The coronavirus disease 2019 pandemic significantly reduced corneal transplantation (CT) rates in Brazil, leading to increased waiting lists. CT rates have not recovered to pre-pandemic levels, indicating long-term implications for patients needing corneal transplants.
Area of Science:
- Ophthalmology
- Transplantation Medicine
- Public Health
Background:
- The coronavirus disease 2019 (COVID-19) pandemic caused widespread disruption to healthcare systems globally.
- Corneal transplantation (CT) services faced challenges due to lockdowns, resource reallocation, and patient-related fears.
Purpose of the Study:
- To evaluate the impact of the COVID-19 pandemic on corneal transplantation (CT) in Brazil.
- To compare CT rates, waiting list dynamics, and surgical procedures before and during the pandemic.
Main Methods:
- Retrospective analysis of corneal transplantation data from Hospital Oftalmológico de Sorocaba (HOS), Brazil.
- Comparison of prepandemic (Jan 2019-Mar 2020) data with pandemic periods (Apr-Sep 2020 and Oct 2020-Apr 2021).
- Inclusion of national and state-level keratoplasty and waiting list data.
Main Results:
- Monthly CT rates decreased significantly at HOS (-14.7%), São Paulo state (-19.1%), and Brazil (-30.1%) post-pandemic resumption.
- Corneal transplantation waiting lists increased significantly both regionally and nationally.
- Post-resumption, endothelial keratoplasty proportions declined, while penetrating keratoplasty proportions increased.
Conclusions:
- Corneal transplantation numbers dropped significantly across all levels (local, regional, national) during the pandemic.
- The increase in CT waiting lists has significant long-term implications for patient access to sight-restoring procedures.
- Substantial increases in monthly CT rates are needed to return waiting lists to prepandemic levels within two years.
Purpose:
The purpose of this study was to evaluate the impact of the coronavirus disease 2019 pandemic on corneal transplantation (CT) in Brazil.
Methods:
Data from patients who underwent CT at the Hospital Oftalmológico de Sorocaba (HOS), Brazil, were analyzed. National and state numbers of keratoplasties, patients added to the CT waiting list, and total patients on the waiting list were also obtained. Baseline prepandemic (from January 1, 2019, to March 31, 2020) data were compared with 2 time frames of the coronavirus disease 2019 pandemic: elective CT suspension period (between April 1, 2020, and September 31, 2020) and after elective CT resumption (between October 1, 2020, and April 30, 2021).
Results:
Despite elective CT resumption after the moratorium, the monthly CT rates did not return to baseline at HOS (-14.7%, P = 0.007), São Paulo state (-19.1%, P = 0.001), or Brazil (-30.1%, P < 0.001). The waiting list increased significantly regionally (P < 0.001) and nationally (P < 0.001). Among optical keratoplasties performed at HOS after resuming elective CTs, the proportion of endothelial keratoplasties declined from 38.2% to 30.0% (P < 0.001), whereas penetrating keratoplasties increased from 33.2% to 39.5% (P < 0.001) when comparing with prepandemic data.
Conclusions:
Keratoplasty numbers dropped significantly locally, regionally, and nationally. Hence, the CT waiting lists had a progressive increase, with significant long-term implications. An estimated increment on monthly CT rates of approximately 34% in São Paulo state, and 91% in Brazil, is required for the CT waiting list to get back to prepandemic numbers over the next 2 years.
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