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COBRA: COde Blue Retrospective Audit in a metropolitan hospital
Robert A Paul1,2, Craig Beaman3, David A West2
1Intensive Care Unit, Alfred Health, Melbourne, Victoria, Australia.
Insights
Inhospital cardiac arrest (IHCA) is uncommon and deadly. A medical emergency team (MET) did not change IHCA prevalence, but early detection and intervention improved survival outcomes.
Area of Science:
- Cardiology
- Critical Care Medicine
- Hospital Management
Background:
- Inhospital cardiac arrest (IHCA) presents a significant clinical challenge.
- High mortality rates are associated with IHCA.
- Understanding IHCA management and outcomes is crucial for improving patient care.
Purpose of the Study:
- To analyze the management and outcomes of IHCA.
- To evaluate the impact of introducing a Medical Emergency Team (MET) on IHCA prevalence.
- To identify factors influencing survival to hospital discharge after IHCA.
Main Methods:
- Retrospective review of 176 adult IHCA cases over five years.
- Inclusion of patients receiving cardiopulmonary resuscitation across various hospital settings.
- Statistical analysis using average treatment effect (ATE) and control charts to assess outcomes and prevalence over time.
Main Results:
- Inhospital cardiac arrest (IHCA) had a high mortality rate, with 65.3% of patients dying during hospitalization.
- The introduction of a dedicated MET service did not alter IHCA prevalence.
- Survival to discharge was associated with initial rhythms of ventricular tachycardia (VT) or ventricular fibrillation (VF), cardiac monitoring, and shorter times to return of spontaneous circulation.
Conclusions:
- IHCA remains an uncommon but high-mortality event.
- A dedicated MET service did not reduce IHCA prevalence in this study.
- Key factors for improved survival include initial shockable rhythms (VT/VF), continuous cardiac monitoring, and prompt resuscitation efforts.
Background:
Inhospital cardiac arrest (IHCA) is an uncommon but challenging problem.
Aims:
To investigate the management and outcomes of IHCA, and to investigate the effect of introducing a medical emergency team (MET) on IHCA prevalence.
Methods:
Retrospective medical record review of 176 adult IHCA episodes at Box Hill Hospital, a university-affiliated public hospital in metropolitan Melbourne, from July 2012 to June 2017. Inpatients receiving cardiopulmonary resuscitation for IHCA, in inpatient wards, intensive care unit, cardiac catheterisation laboratory and operating theatres were included. Data collected included demographics, resuscitation management and outcomes. Average treatment effect (ATE) was derived from margins estimates and linear regression fitted to hospital outcome, adjusted for IHCA factors. An exponentially weighed moving average control chart was used to explore IHCA prevalence over time.
Results:
There were 65.3% of IHCA patients who died in hospital. IHCA prevalence was unchanged after the introduction of a dedicated MET service. Factors associated with higher likelihood of survival to discharge were initial cardiac of rhythm ventricular tachycardia (VT) (ATE 0.10 (95% CI = -0.03 to 0.25)) or ventricular fibrillation (VF) (ATE 0.28 (95% CI = 0.11-0.46)), cardiac monitoring at the time of arrest (ATE 0.06 (95%CI = -0.04 to 0.16)) and time to return of spontaneous circulation (ATE 0.023 (95% CI = 0.015-0.031)).
Conclusions:
IHCA is uncommon and is associated with high mortality. IHCA prevalence was unchanged after the introduction of a dedicated MET service. Factors associated with improved survival to hospital discharge were initial rhythm VT or VF, cardiac monitoring and shorter resuscitation times.
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