Related Experiment Video
Updated: Oct 11, 2025

05:52
Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
15.1K
Descriptive Longitudinal Analysis of Stereotypy and Corresponding Changes in Psychotropic Medication
Drew Piersma1, Marisela Aguilar1, Haley Seibert1
1Drake University, Des Moines, IA, USA.
Developmental Neurorehabilitation
|December 6, 2021
Summary
Stereotypic behavior in adults with autism spectrum disorder (ASD) persists, even with psychotropic medication changes. Further research is needed to understand these complex behaviors.
Area of Science:
- Neuroscience
- Developmental Psychology
- Behavioral Science
Background:
- Psychotropic medications are frequently prescribed for individuals with intellectual and developmental disabilities (IDDs) exhibiting challenging behaviors like aggression and stereotypy.
- Limited understanding exists regarding the impact of these medications on behavior in this population.
Purpose of the Study:
- To describe the presentation of stereotypic behavior in three individuals with autism spectrum disorder (ASD).
- This study is part of a larger investigation into psychotropic medication regimen changes and their effects on challenging behaviors.
Main Methods:
- Stereotypy was assessed through weekly, one-hour direct observations.
- Stereotypy was also measured during functional analyses (control and ignore conditions) of challenging behaviors.
- Medication regimen changes preceded the functional analyses.
Main Results:
- Observed patterns of stereotypy showed non-significant variations over time.
- Instances of stereotypy sometimes appeared to correlate with changes in psychotropic medication.
Conclusions:
- Stereotypy is suggested to persist into adulthood in individuals with ASD.
- Additional research is necessary to fully comprehend the persistence and influencing factors of stereotypy.
More Related Videos
Related Concept Videos
Longitudinal Research
12.7K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.7K
Drug Therapy
116
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
116
Longitudinal Studies
280
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
280
Psychosis: Goals of Pharmacotherapy
255
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
255
Psychosis and Antipsychotic Drugs: Overview
525
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
525
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance
338
The elimination half-life and drug clearance of drugs following nonlinear kinetics can vary with dosage. The Michaelis-Menten parameters and drug concentration influence these factors. As the dose increases, the elimination half-life tends to lengthen, resulting in a reduction in clearance and a disproportionately larger area under the curve. The total clearance can be derived from the Michaelis-Menten equation for drugs following a one-compartment model.
A study on guinea pigs examined the...
A study on guinea pigs examined the...
338

