Bi-atrial thrombus straddling a patent foramen ovale with bilateral embolization: A therapeutic challenge

Abhishek Dattani1,2, Kassem Safwan1, Mohammedimran Ansari1

  • 1Department of Cardiology, Glenfield Hospital, Leicester, UK.

Insights

A rare cardiac thrombus caused a stroke and pulmonary emboli in a 55-year-old male. This case highlights the need for multidisciplinary care in managing complex cardiovascular and neurological conditions.

Area of Science:

  • Cardiology
  • Neurology
  • Radiology

Background:

  • Ischemic stroke is a major global health concern, with cardiac sources accounting for a significant proportion of cases.
  • Intra-cardiac thrombus formation can lead to embolic events, including stroke and pulmonary embolism.
  • Patent Foramen Ovale (PFO) is a potential pathway for paradoxical embolism.

Observation:

  • A 55-year-old male presented with acute ischemic stroke and bilateral pulmonary emboli.
  • Transesophageal echocardiography revealed an intra-cardiac thrombus straddling a patent foramen ovale.
  • The patient's clinical presentation posed a management dilemma due to the risk of hemorrhagic transformation.

Findings:

  • The intra-cardiac thrombus was identified as the source of both the ischemic stroke and pulmonary emboli.
  • Echocardiography proved crucial in visualizing the thrombus and its relationship with the PFO.
  • The case underscores the complexity of managing embolic events originating from cardiac sources.

Implications:

  • This case emphasizes the importance of a comprehensive diagnostic approach, including advanced imaging, in identifying the source of embolic strokes.
  • It highlights the challenges in managing patients with concurrent ischemic stroke and pulmonary embolism due to conflicting treatment risks.
  • The findings advocate for a multidisciplinary team approach involving cardiology, neurology, and other specialists to navigate complex clinical scenarios lacking clear treatment guidelines.

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
68
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
55
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
72
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
177