New system for archiving integrative structures

Area of Science:

• Structural biology
• Biochemistry
• Computational biology

Background:

• Complex biological assemblies are crucial for understanding cellular functions.
• Integrative approaches, combining multiple experimental methods, are increasingly used to determine their structures.
• Publicly archiving and sharing these structures is essential for scientific progress.

Purpose of the Study:

• To introduce PDB-Dev, a dedicated system for archiving and disseminating integrative structures.
• To detail the data standards, software tools, and infrastructure supporting PDB-Dev.
• To ensure adherence to FAIR principles for enhanced data accessibility and reusability.

Main Methods:

• Development of a standalone archiving system (PDB-Dev).
• Implementation of data standards and software tools for data collection, processing, and archiving.
• Adoption of FAIR (Findable, Accessible, Interoperable, Reusable) principles.

Main Results:

• PDB-Dev is established as a central repository for integrative structures.
• The system's infrastructure supports efficient data management.
• Data standards and tools facilitate the archiving process.

Conclusions:

• PDB-Dev provides a crucial resource for the structural biology community.
• The system promotes open science by making integrative structure data freely accessible.
• Adherence to FAIR principles enhances the value and impact of archived structural data.