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Stress Hyperglycemia Ratio may Portend Poor Outcomes in COVID-19

Rohan Magoon1, Jes Jose2

  • 1Department of Cardiac Anaesthesia, Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|December 6, 2021
PubMed

Insights

The Stress Hyperglycemia Ratio may indicate worse outcomes for patients with COVID-19. This simple ratio could help predict patient prognosis in critical care settings.

Area of Science:

  • Critical Care Medicine
  • Endocrinology
  • Infectious Diseases

Background:

  • COVID-19 is associated with significant morbidity and mortality.
  • Stress hyperglycemia is a common complication in critically ill patients.
  • Predictive markers for COVID-19 severity are crucial for patient management.

Purpose of the Study:

  • To investigate the association between the Stress Hyperglycemia Ratio (SHR) and patient outcomes in COVID-19.
  • To determine if SHR can serve as a prognostic indicator in COVID-19 patients.

Main Methods:

  • Retrospective analysis of COVID-19 patient data.
  • Calculation of the Stress Hyperglycemia Ratio (serum glucose/HbA1c).
  • Correlation of SHR with clinical outcomes such as mortality and length of stay.

Main Results:

  • Patients with higher Stress Hyperglycemia Ratios exhibited poorer clinical outcomes.
  • SHR was found to be a significant predictor of adverse events in COVID-19.
  • A statistically significant correlation was observed between elevated SHR and increased mortality.

Conclusions:

  • The Stress Hyperglycemia Ratio is a potential biomarker for predicting poor outcomes in COVID-19 patients.
  • SHR offers a simple yet effective tool for risk stratification in critical care.
  • Further prospective studies are warranted to validate these findings.

Keywords:
Admission blood glucoseCOVID-19Diabetes mellitusPoor outcomesRelative hyperglycemiaStress hyperglycemia ratio

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