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Updated: Oct 11, 2025

Translational Rabbit Model of Chronic Cardiac Pacing
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A pacemaker pocket mass has many faces.

James Milner1, Francisco Gonçalves1, Lino Gonçalves1,2

  • 1Cardiology Department, Centro Hospitalar e Universitário de Coimbra.

Journal of Cardiology Cases
|December 6, 2021
PubMed
Summary
This summary is machine-generated.

Malignant neoplasms rarely develop at pacemaker sites. This case highlights a cutaneous lymphoplasmacytic lymphoma presenting as a pacemaker pocket mass, emphasizing the need for high clinical suspicion and histological evaluation.

Keywords:
Lymphoplasmacytic lymphomaMalignant neoplasmPacemaker pocket

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Area of Science:

  • Oncology
  • Dermatology
  • Pathology

Background:

  • Malignant neoplasms arising at pacemaker implantation sites are exceptionally rare.
  • Pacemaker pocket masses typically present as hematomas or infections.

Observation:

  • A 78-year-old male presented with a pacemaker pocket mass and discomfort after trauma.
  • Initial treatment for presumed hematoma without histological analysis.
  • Recurrent ulcerated mass necessitated biopsy, revealing lymphoplasmacytic lymphoma.

Findings:

  • This is the first reported case of cutaneous lymphoplasmacytic lymphoma presenting as a pacemaker pocket mass.
  • Lymphoplasmacytic lymphoma, an indolent Non-Hodgkin lymphoma, can manifest with cutaneous involvement.
  • Histological examination is crucial for diagnosing rare malignancies in pacemaker sites.

Implications:

  • Highlights the importance of thorough pacemaker site inspection.
  • Underscores the necessity of adequate histological characterization for suspected malignancies.
  • Stresses the need for a high degree of clinical suspicion in pacemaker pocket mass evaluation.