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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

575
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
575
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

76
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
76
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

558
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
558

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Related Experiment Video

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Intra-Omental Islet Transplantation Using h-Omental Matrix Islet filliNG hOMING
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Hydrogen: Potential Applications in Solid Organ Transplantation.

Fuxun Yang1, Yu Lei1, Rongan Liu1

  • 1Department of ICU, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.

Oxidative Medicine and Cellular Longevity
|December 6, 2021
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Summary
This summary is machine-generated.

Hydrogen may protect organs during transplantation by reducing ischemia reperfusion injury (IRI). This review explores hydrogen

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Area of Science:

  • Biomedical Science
  • Organ Transplantation
  • Oxidative Stress

Background:

  • Ischemia reperfusion injury (IRI) is a major challenge in organ transplantation.
  • IRI contributes to organ damage and graft failure.
  • Effective organ protection strategies are crucial for improving transplant outcomes.

Purpose of the Study:

  • To review the protective effects of hydrogen against IRI in organ transplantation.
  • To explore hydrogen's potential as a therapeutic agent for organ protection.
  • To provide insights for future clinical applications of hydrogen in transplantation.

Main Methods:

  • Literature review of studies investigating hydrogen's role in IRI.
  • Analysis of existing research on hydrogen's antioxidant, anti-inflammatory, and antiapoptotic properties.
  • Synthesis of findings related to hydrogen's efficacy in preclinical models of IRI.

Main Results:

  • Hydrogen exhibits significant antioxidant, anti-inflammatory, and antiapoptotic effects.
  • These properties suggest a protective role for hydrogen against IRI.
  • Evidence indicates potential benefits of hydrogen in mitigating IRI-induced organ damage.

Conclusions:

  • Hydrogen shows promise as a protective agent against IRI in organ transplantation.
  • Further clinical studies are warranted to validate hydrogen's therapeutic potential.
  • Hydrogen may offer a novel strategy for enhancing organ viability and transplant success.