Related Experiment Video
Updated: Oct 11, 2025

05:18
Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
Published on: July 12, 2024
447
Pulmonary function parameters among marble industry workers in Lahore, Pakistan.
Imran Maqsood Butt1, Tajammal Mustafa2, Shahnaz Rauf3
1Institute of Public Health, Lahore, 54000, Pakistan.
F1000Research
|December 6, 2021
Summary
Occupational exposure to marble dust significantly impairs lung function in workers, leading to decreased forced vital capacity and forced expiratory volume. Prolonged work experience increases the risk of developing these obstructive lung diseases.
Area of Science:
- Occupational Health
- Pulmonology
- Environmental Health
Background:
- Occupational exposure to dust particles, particularly crystalline silica in marble dust, is a significant health concern.
- Marble stone workers face direct contact with marble dust, contributing to a rising prevalence of obstructive lung diseases.
Purpose of the Study:
- To compare pulmonary function parameters between marble workshop workers and age-matched healthy individuals in Lahore, Pakistan.
- To assess the impact of marble dust exposure on lung function tests.
Main Methods:
- A comparative study involving 164 male participants (82 marble workers, 82 healthy controls).
- Data collection via in-person interviews and structured questionnaires.
- Pulmonary function tests using Spiro Lab spirometry to evaluate FVC%, FEV1, and FEV1/FVC ratio.
Main Results:
- Marble workers showed a highly significant decrease (P < 0.001) in FVC%, FEV1, and FEV1/FVC ratio compared to healthy individuals.
- 71% of marble workers exhibited abnormal pulmonary parameters, with 34% showing restrictive pulmonary impairment.
- Over 15 years of work experience significantly increased the risk of abnormal pulmonary function (P < 0.001).
Conclusions:
- Continuous exposure to marble dust leads to deterioration of lung function in marble workers.
- Marble dust exposure is strongly associated with obstructive lung diseases and pulmonary impairment.
Related Concept Videos
Pulmonary Function Tests
457
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
457
Factors Affecting Pulmonary Ventilation
1.9K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.9K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K
Pulmonary Tuberculosis I
390
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
390

