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Gene Therapy Knowledge and Attitude Among Healthcare Professionals: A Cross-Sectional Study

Maha M AlRasheed1, Hatoon AlAli2, Abdulrahman F Alsuwaid1

  • 1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Frontiers in Public Health
|December 6, 2021
PubMed

Insights

Healthcare professionals in Saudi Arabia have limited knowledge but positive attitudes towards gene therapy. Educational programs focusing on safety and social acceptance are recommended.

Area of Science:

  • Biotechnology
  • Medical Genetics
  • Pharmacology

Background:

  • Gene therapy represents a novel therapeutic frontier with significant potential.
  • Understanding healthcare professionals' perspectives is crucial for successful implementation.

Purpose of the Study:

  • To evaluate knowledge, attitudes, and concerns regarding gene therapy among healthcare professionals in Saudi Arabia.
  • To identify factors influencing knowledge and attitudes towards gene therapy.

Main Methods:

  • An online cross-sectional survey was conducted with 419 pharmacists and physicians in Saudi Arabia.
  • Data were collected from December 2018 to March 2019.
  • Statistical analyses were performed to assess knowledge, attitudes, and associated factors.

Main Results:

  • Participants demonstrated limited knowledge of gene therapy (mean score 3.8/10).
  • Higher knowledge was associated with younger age, male gender, advanced degrees (Master's, Ph.D.), and Canadian education.
  • Approximately 55% expressed concerns, with genetics training at college identified as the preferred educational method.

Conclusions:

  • Pharmacists and physicians in Saudi Arabia exhibit a gap in gene therapy knowledge despite a positive attitude.
  • Targeted educational initiatives are necessary to enhance understanding, particularly concerning safety and societal acceptance.
  • Future strategies should prioritize comprehensive training programs for healthcare providers.

Keywords:
Saudi Arabiaattitudegene therapyhealthcare professionalsknowledge

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