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Updated: Oct 11, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Patient selection, procedural planning and interventional guidance for non-valvular structural intervention
Federico DE Marco1, Andrea Romano2, Matteo Casenghi1
1Department of Clinical and Interventional Cardiology, IRCCS Policlinico San Donato, Milan, Italy.
Percutaneous structural interventions for heart defects offer a safe alternative to surgery. Careful pre-procedure planning and imaging are key to minimizing complications and improving outcomes in patients undergoing procedures like patent foramen ovale closure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Percutaneous non-valvular structural interventions are increasingly utilized as alternatives to pharmacological or surgical treatments.
- These procedures, including patent foramen ovale closure and septal defect repair, are typically performed in young, healthy individuals.
- Minimizing procedural and device-related complications is essential for optimal patient outcomes.
Purpose of the Study:
- To review current evidence on patient selection for percutaneous non-valvular structural interventions.
- To outline best practices for pre-procedural planning and intra-procedural imaging.
- To guide physicians in identifying patients who will benefit most from these interventions.
Main Methods:
- Systematic review of existing literature on percutaneous non-valvular structural interventions.
- Analysis of data concerning patient selection criteria.
- Evaluation of imaging techniques and procedural guidance strategies.
Main Results:
- Careful pre-procedural planning and accurate intra-procedural imaging are critical for reducing complications.
- Evidence supports the efficacy of these interventions in selected patient populations.
- Physician guidance is crucial for determining optimal patient candidates.
Conclusions:
- Percutaneous non-valvular structural interventions are effective and safe alternatives when appropriately planned and executed.
- Optimizing patient selection and procedural techniques enhances outcomes.
- Further research may refine patient selection and procedural guidance for these interventions.
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