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Primary nasopharyngeal papillary adenocarcinoma: A CARE-compliant case report
Chih-Hsuan Shen1, Shih-Lun Chang1,2, Sheng-Tsung Chang3
1Department of Otorhinolaryngology, Chi Mei Medical Center, Tainan, Taiwan.
Rationale:
Primary nasopharyngeal papillary adenocarcinoma is a rare nasopharyngeal neoplasm with a good prognosis and a low propensity for regional recurrence. To date, only few cases of primary nasopharyngeal papillary adenocarcinoma have been reported in the literature.
Patient Concerns:
A 24-year-old female patient presented with intermittent hemoptysis and blood tinge nasal discharge.
Diagnosis:
An exophytic and pedunculated mass over the roof of the nasopharynx was found on nasopharyngoscope. Biopsy was done and the pathology confirmed well-differentiated primary nasopharyngeal papillary adenocarcinoma, strongly positive for CK7, and transcription termination factor 1; but negative for thyroglobulin. The final diagnosis was primary nasopharyngeal papillary adenocarcinoma, well-differentiated, pT1N0M0, stage I.
Interventions:
The patient underwent excision of nasopharyngeal tumor under sinuscopic assistance.
Outcomes:
: No local recurrence or distant metastasis was noted during the 6 months of follow-up.
Lessons:
We aim at highlighting the importance of a thorough differential diagnosis of nasopharyngeal tumor. Further investigation is still needed for providing evidence to standardize the treatment protocol.
