Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Benign schwannomas: pathologic basis for CT inhomogeneities.

L M Cohen, A M Schwartz, S D Rockoff

    AJR. American Journal of Roentgenology
    |July 1, 1986
    PubMed
    Summary

    Benign schwannomas can show mixed CT attenuation, previously thought to indicate malignancy. Pathological findings explain this CT appearance, showing inhomogeneity can be benign.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Regulation of Transcription by RNA Polymerase III Promotors in the Norm and Pathology].

    Molekuliarnaia biologiia·2024
    Same author

    Cut from the same cloth: RNAs transcribed from regulatory elements.

    Biochimica et biophysica acta. Gene regulatory mechanisms·2024
    Same author

    [Full and D-Box-Deficient PTTG1 Isoforms: Effects on Cell Proliferation].

    Molekuliarnaia biologiia·2022
    Same author

    [The Minor T Allele of the Single Nucleotide Polymorphism rs 13360222 Decreases the Activity of the HAVCR2 Gene Enhancer in a Cell Model of Human Macrophages].

    Molekuliarnaia biologiia·2022
    Same author

    [Functional Characteristics of Long Noncoding RNAs Containing Sequences of Mobile Genetic Elements].

    Molekuliarnaia biologiia·2020
    Same author

    [The Influence of the Minor Short Isoform of Securin (PTTG1) on Transcription is Significantly Different from the Impact of the Full Isoform].

    Molekuliarnaia biologiia·2020

    Area of Science:

    • Radiology
    • Pathology
    • Oncology

    Background:

    • Computed tomography (CT) is crucial for tumor characterization.
    • Mixed CT attenuation in tumors has often been associated with malignancy.
    • Schwannomas are nerve sheath tumors with variable imaging features.

    Purpose of the Study:

    • To correlate the histological features of benign schwannomas with their appearance on CT scans.
    • To investigate the cause of mixed CT attenuation in pathologically confirmed benign schwannoma cases.

    Main Methods:

    • Retrospective review of four pathologically proven benign schwannoma cases.
    • Comparison of histological findings with corresponding CT imaging characteristics.

    Main Results:

    • All four benign schwannomas exhibited mixed CT attenuation.
    • Histological examination revealed areas of hypocellularity, dense cellularity, xanthomatous changes, and cystic degeneration contributing to CT inhomogeneity.
    • These pathological findings provide an explanation for the observed mixed attenuation patterns.

    Conclusions:

    • Benign schwannomas can present with mixed attenuation on CT scans.
    • CT inhomogeneity in schwannomas can be attributed to specific pathological features.
    • Mixed attenuation on CT does not exclusively indicate malignancy and requires pathological correlation.

    Related Experiment Videos