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Recent Insights into COVID-19 in Children and Clinical Recommendations

Jairo Castellar-López1, Wendy Villamizar-Villamizar2, Aldo Amaranto-Pallares2

  • 1Faculty of Exact and Natural Sciences, Grupo de Investigación Avanzada en Biomedicina, Universidad Libre Barranquilla, Barranquilla, Colombia.

Current Pediatric Reviews
|December 7, 2021
PubMed

Insights

Pediatric coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) present unique challenges. This review synthesizes current knowledge on SARS-CoV-2 in children, focusing on epidemiology, clinical features, and treatment guidelines.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Virology

Background:

  • Pediatric coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) are significant global health concerns.
  • Understanding SARS-CoV-2 infection in children requires a comprehensive review of epidemiological, clinical, and laboratory data.

Purpose of the Study:

  • To provide recent insights into SARS-CoV-2 infection in children.
  • To highlight key features of pediatric COVID-19 and its relationship with MIS-C and Kawasaki disease.
  • To summarize current treatment guidelines for COVID-19 in children.

Main Methods:

  • Review of global reports on pediatric COVID-19 and MIS-C.
  • Synthesis of epidemiological, clinical, and laboratory findings.
  • Compilation of treatment guidelines from various institutional protocols, expert consensus, and official statements.

Main Results:

  • Key features of SARS-CoV-2 infection in children are identified.
  • The relationship between MIS-C and Kawasaki disease is explored.
  • Treatment guidelines from WHO, CDC, and regional pediatric associations are summarized.

Conclusions:

  • Current understanding of pediatric COVID-19 and MIS-C is evolving.
  • Further research is needed to elucidate the pathogenesis of pediatric COVID-19.
  • Standardized treatment protocols and ongoing research are crucial for managing pediatric COVID-19.

Keywords:
COVID-19SARS-CoV-2childreninflammationkawasaki diseasemultisystem inflammatory syndrome

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