COVID-19: comprehensive review on mutations and current vaccines

Area of Science:

• Virology
• Epidemiology
• Public Health

Background:

• Viral outbreaks pose a significant global health threat, impacting human health, society, and economies.
• Coronavirus disease-19 (COVID-19), caused by SARS-CoV-2, has resulted in millions of infections and deaths worldwide.
• The continuous emergence of new variants necessitates ongoing research into effective countermeasures.

Purpose of the Study:

• To review novel mutations in coronaviruses.
• To provide updates on therapeutic and prophylactic strategies for COVID-19.
• To summarize clinical manifestations, diagnosis, and management of COVID-19.

Main Methods:

• Literature review of recent studies on coronaviruses and COVID-19.
• Analysis of data on viral mutations and their impact.
• Synthesis of information on clinical management and treatment options.

Main Results:

• Highlighting novel mutations in SARS-CoV-2.
• Discussing the efficacy of current and emerging vaccines and therapies.
• Summarizing diagnostic and clinical management approaches for COVID-19 patients.

Conclusions:

• Effective prevention, early detection, and prompt treatment are crucial for controlling the COVID-19 pandemic.
• Continuous development of novel therapies and vaccines is essential to address evolving viral strains.
• A comprehensive understanding of viral mutations and clinical management is vital for global health security.