Related Experiment Video

Updated: Jul 30, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

7.2K

[Longitudinal Direct Closure of Mitral Anterior Leaflet Large Perforation for Infective Endocarditis:Report of a

Sei Morizumi1, Yoshiharu Enomoto, Kaori Ikeda

  • 1Department of Cardiovascular Sugery, Ibaraki Prefectural Central Hospital and Ibaraki Cancer Center, Kasama, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|December 8, 2021
PubMed

Insights

A 65-year-old man with infective endocarditis underwent successful mitral valve repair for a large perforation. Direct primary closure of the anterior mitral leaflet perforation effectively controlled mitral regurgitation.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Infectious Diseases

Background:

  • Infective endocarditis can cause significant valvular damage, leading to regurgitation.
  • Mitral valve involvement in endocarditis poses complex surgical challenges.
  • Aortic regurgitation can directly impact adjacent mitral valve structures.

Observation:

  • A 65-year-old male presented with infective endocarditis affecting the mitral valve.
  • Severe mitral regurgitation and moderate aortic regurgitation were identified via echocardiography.
  • Aortic regurgitant jet caused thickening and a 17mm perforation of the anterior mitral leaflet.

Findings:

  • Staphylococcus epidermidis was identified in blood cultures.
  • Successful mitral valve repair was achieved through direct primary closure of the leaflet perforation using a 5-0 polypropylene suture.
  • Aortic valve replacement was also performed concurrently.
  • Mitral regurgitation was effectively controlled post-repair.

Implications:

  • Direct primary closure is a simple and effective technique for managing anterior mitral leaflet perforations caused by endocarditis.
  • This approach can successfully restore valve function and prevent further complications.
  • Timely surgical intervention is crucial for managing severe valvular damage in infective endocarditis.

More Related Videos

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence10:52

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence

Published on: December 23, 2022

3.9K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

1.8K

Related Concept Videos

Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...