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Related Concept Videos

Obesity01:24

Obesity

683
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
683
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

13
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
13
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

13
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

15
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
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Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

775
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
775
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

196
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
196

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Updated: Oct 10, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

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Published on: May 30, 2025

461

Research priority setting in obesity: a systematic review.

Halima Iqbal1,2, Rosemary R C McEachan2, Jane West2

  • 1Faculty of Health Studies, University of Bradford, Richmond Road, Bradford, BD7 1DP UK.

Zeitschrift Fur Gesundheitswissenschaften = Journal of Public Health
|December 8, 2021
PubMed
Summary

Effective obesity research priority setting requires public involvement and rigorous evaluation. Current studies often lack comprehensive approaches and inclusivity, highlighting a need for improved methodologies in setting research priorities for obesity.

Keywords:
obesityobesity research agendaresearch priority setting

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Area of Science:

  • Public Health
  • Health Services Research
  • Obesity Research

Background:

  • High-quality obesity research priority setting is crucial for policy relevance and efficiency.
  • A systematic review is needed to assess adherence to good practice principles in existing obesity research priority setting studies.

Purpose of the Study:

  • To identify obesity research priority setting studies.
  • To evaluate these studies against established good practice principles.

Main Methods:

  • A comprehensive literature search was conducted across multiple databases and grey literature.
  • Nine principles of good practice in research priority setting were used as a framework for evaluation.

Main Results:

  • Thirteen studies were included, reporting engagement with policymakers, researchers, and healthcare professionals.
  • Public involvement was present in only six studies; no study met all nine good practice criteria.
  • Common limitations included a lack of comprehensive approach, inclusivity, and process evaluation.

Conclusions:

  • Obesity research priority setting exercises must incorporate public engagement.
  • Future priority setting studies need robust evaluation to ensure high quality and adherence to best practices.