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Related Experiment Video

Updated: Oct 10, 2025

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence

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DNA Profiling in Forensic Science: A Review.

Jaya Lakshmi Bukyya¹, M L Avinash Tejasvi², Anulekha Avinash³

¹Department of Oral Medicine and Radiology, Tirumala Institute of Dental Sciences, Nizamabad, Telangana, India.

Global Medical Genetics

|December 8, 2021

Summary

Forensic investigators utilize unique deoxyribonucleic acid (DNA) markers found in cells for identifying individuals at crime scenes. This review examines the application and limitations of these genetic markers in forensic science.

Keywords:

base pairs deoxyribonucleic acid polymerase chain reaction simple sequence repeat single-nucleotide polymorphism

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Area of Science:

Forensic Science
Genetics
Molecular Biology

Background:

Deoxyribonucleic acid (DNA) is a unique identifier present in most human cells.
Individuals leave behind DNA traces in various environments.
DNA analysis has revolutionized forensic investigations.

Purpose of the Study:

To review the application of genetic markers in forensic investigations.
To discuss the capabilities and limitations of DNA evidence in criminal identification.

Main Methods:

Review of scientific literature on DNA profiling techniques.
Analysis of case studies utilizing genetic markers for identification.
Examination of current forensic DNA analysis methodologies.

Main Results:

Genetic markers provide powerful tools for victim and perpetrator identification.
DNA analysis is crucial for establishing links between suspects and crime scenes.
Limitations include sample degradation, contamination, and interpretation challenges.

Conclusions:

Genetic markers are indispensable in modern forensic science.
Understanding the limitations of DNA analysis is critical for accurate interpretation.
Continued research is needed to enhance DNA profiling techniques and overcome challenges.