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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Accessory Structures of the Skin: Nails01:05

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Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
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Related Experiment Video

Updated: Oct 10, 2025

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
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Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

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Nail-fold capillaroscopy for the dermatologists.

Chander Grover1, Deepak Jakhar2, Arzoo Mishra1

  • 1Department of Dermatology and STD, University College of Medical College and GTB Hospital, New Delhi, India.

Indian Journal of Dermatology, Venereology and Leprology
|December 8, 2021
PubMed
Summary
This summary is machine-generated.

Nail fold capillaroscopy is a valuable diagnostic tool for microvascular changes in various diseases. Its utility has expanded beyond connective tissue diseases, aiding dermatologists in diagnosis and prognosis.

Keywords:
Capillaroscopecapillaroscopydermatologynail fold capillaroscopynail fold videocapillaroscopy

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Area of Science:

  • Dermatology
  • Microcirculation Research
  • Diagnostic Imaging

Background:

  • Nail fold microcirculation offers accessible insights into microangiopathies.
  • Characterizing microvascular changes aids disease diagnosis and prognosis.
  • Nail fold capillaroscopy's diagnostic utility has significantly advanced.

Purpose of the Study:

  • To provide dermatologists with comprehensive knowledge on nail fold capillaroscopy.
  • To review the expanding applications of nail fold capillaroscopy in various diseases.
  • To highlight the importance of nail fold capillaroscopy in systemic sclerosis diagnosis.

Main Methods:

  • A PubMed search was conducted using keywords: "nail fold capillaries" and "nail fold capillaroscopy".
  • Retrieved articles were categorized into reviews and clinical studies.
  • Data from selected articles were analyzed and presented narratively.

Main Results:

  • Nail fold capillaroscopy is increasingly utilized beyond connective tissue diseases.
  • Its application is being explored in systemic and dermatological conditions.
  • Inclusion in systemic sclerosis criteria has boosted dermatological interest.

Conclusions:

  • Nail fold capillaroscopy is an evolving and crucial diagnostic method for microvascular assessment.
  • Dermatologists can leverage this technique for enhanced patient diagnosis and management.
  • Further exploration of its role in diverse pathologies is warranted.