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Updated: Jun 23, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

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SCREENER, an educational game for teaching the Drug Discovery and Development process.

F Noël^1,2,3, G Xexéo^4,5, E Mangeli^4,6

¹Laboratório de Farmacologia Bioquímica e Molecular, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas

|December 8, 2021

Summary

A new science game, SCREENER, was developed to educate students and professionals on the complex Drug Discovery and Development (DDD) process. This engaging board and card game simulates DDD stages, offering a unique training tool.

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Area of Science:

Pharmacology and Medicinal Chemistry
Pharmaceutical Sciences
Educational Technology

Background:

Educational games are a growing trend, but a gap exists in training for the Drug Discovery and Development (DDD) process.
Existing training methods may not adequately engage learners in the complexities of DDD.

Purpose of the Study:

To introduce SCREENER, an educational science game designed to teach the Drug Discovery and Development (DDD) process.
To provide an engaging and challenging learning experience for postgraduate students and professionals in related fields.

Main Methods:

SCREENER is a hybrid board and card game simulating DDD from target validation to regulatory registration.
The game involves sequential purchase of 29 task cards across efficacy, safety, pharmacokinetics, and pharmaceutical development.
Bonus/setback cards introduce variability, mimicking real-world DDD challenges; QR codes provide further information.

Main Results:

Initial testing with students indicated the usefulness of SCREENER as a novel educational tool.
The game successfully incorporates decision-making and challenges inherent in drug development.

Conclusions:

SCREENER effectively bridges the educational gap in Drug Discovery and Development (DDD) training.
The game offers a valuable, engaging, and comprehensive learning experience for students and industry professionals.