Related Experiment Video
Updated: Oct 10, 2025

A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy
Published on: November 7, 2017
Occupational Heat Exposure as a Risk Factor for End-Stage Kidney Disease: A Case-Control Study
Celina Doueihy1, Dania Chelala, Hadi Ossaili
1Saint-Joseph University of Beirut (Dr Doueihy, Dr Chelala, Dr Ossaili, Dr Hachem, Dr Aoun), Hotel-Dieu de France Hospital (Dr Chelala), Beirut; Centre Hospitalier du Nord, Mazraat Jnaid (Dr Zeidan, Dr Ghoul); Saint-George Hospital Ajaltoun, Ajaltoun (Dr Aoun), Lebanon.
Objective:
More patients are reaching end-stage kidney disease without evident cause. This study aims to explore occupational risk factors associated with hemodialysis.
Methods:
A multicenter matched case-control study included dialysis patients and age, sex, and diabetes-matched controls (normal kidney function). Conditional logistic regression analysis assessed occupational factors associated with dialysis.
Results:
Two hundred thirty eight hemodialysis patients and 238 controls were included. History of occupational heat exposure (odds ratio [OR] = 1.93; 95% confidence interval [CI]: 1.24 to 3.00), working as a cook (OR = 12; 95% CI: 1.56 to 92.29), as construction worker (OR = 10; 95% CI: 1.28 to 78.12) were associated with higher risk of dialysis. These results were significant in men and in those with kidney disease of unknown etiology.
Conclusions:
Occupational heat exposure was found to be associated with hemodialysis. This is an important step for future development of preventive strategies in high-risk professions.
Related Concept Videos
Chronic Kidney Disease I: Introduction
Chronic Kidney Disease III: Interprofessional Care
Kidney Transplant I: Introduction
Chronic Kidney Disease II: Clinical Manifestations
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury I: Introduction

