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Fluoroquinolones: With great power comes great risk
Tara Kidd1, Stephanie Mitchell, Julie Dehays
1At OhioHealth Marion General Hospital, Tara Kidd is a pharmacy resident, Stephanie Mitchell is a pharmacy APPE student, Julie DeHays is a pharmacy APPE intern, and Erica Wibberley is an antimicrobial stewardship pharmacist.
Nursing
|December 8, 2021
Summary
Fluoroquinolones are effective antibiotics for infections, but nurses must consider their side effects and evolving antibiotic resistance. This guide helps healthcare professionals manage patients on fluoroquinolones.
Area of Science:
- Pharmacology
- Infectious Diseases
- Nursing Practice
Background:
- Fluoroquinolones (FQs) are broad-spectrum antibiotics.
- They are widely used for treating various infections due to efficacy and tolerability.
- Emerging antibiotic resistance and adverse reactions necessitate careful consideration.
Purpose of the Study:
- To review the spectrum of activity of fluoroquinolones.
- To discuss the adverse reactions associated with fluoroquinolone use.
- To provide guidance for nurses caring for patients receiving fluoroquinolones.
Main Methods:
- Literature review of fluoroquinolone pharmacology and clinical use.
- Analysis of current trends in antibiotic susceptibility.
- Synthesis of information to guide nursing care.
Main Results:
- Fluoroquinolones exhibit broad-spectrum activity against many bacterial pathogens.
- Common and serious adverse reactions are identified.
- Antibiotic susceptibility patterns are evolving, impacting treatment choices.
Conclusions:
- Nurses require updated knowledge on fluoroquinolone spectrum of activity and adverse effects.
- Informed patient care is crucial for optimizing treatment outcomes and minimizing risks.
- Monitoring antibiotic susceptibility trends is essential for effective antimicrobial stewardship.
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