Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Selective IgA deficiency.

A W Burks, R W Steele

    Annals of Allergy
    |July 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Selective Immunoglobulin A (IgA) deficiency, the most common immunodeficiency, results from a B lymphocyte defect. Management focuses on associated conditions and careful blood product administration due to potential anti-IgA antibody formation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Early-life gut microbiome and egg allergy.

    Allergy·2018
    Same author

    Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions.

    Nature communications·2017
    Same author

    Component-resolved analysis of IgA, IgE, and IgG4 during egg OIT identifies markers associated with sustained unresponsiveness.

    Allergy·2016
    Same author

    Utility of component analyses in subjects undergoing sublingual immunotherapy for peanut allergy.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2015
    Same author

    Effects of a pre-existing food allergy on the oral introduction of food proteins: findings from a murine model.

    Allergy·2014
    Same author

    Allergen immunotherapy: a new semantic framework from the European Academy of Allergy and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL consensus report.

    Allergy·2013
    Same journal

    Hay fever; a review of the literature for 1945.

    Annals of allergy·2010
    Same journal

    Nasal and sputum smears.

    Annals of allergy·2010
    Same journal

    Determination of penicillin-susceptible strains of bacteria.

    Annals of allergy·2010
    Same journal

    Fleabite reactions; clinical and experimental observations and effect of histamine-azoprotein therapy.

    Annals of allergy·2010
    Same journal

    D.H.E. 45 (dihydroergotamine) in the treatment of allergic megraine.

    Annals of allergy·2010
    Same journal

    Antigenicity of proteins in relation to allergy.

    Annals of allergy·2010
    See all related articles

    Area of Science:

    • Immunology
    • Clinical Medicine

    Background:

    • Selective Immunoglobulin A (IgA) deficiency is the most prevalent primary immunodeficiency.
    • It disproportionately affects individuals with allergies, autoimmune diseases, gastrointestinal disorders, and recurrent respiratory infections.

    Purpose of the Study:

    • To summarize the key aspects of Selective IgA deficiency.
    • To highlight associated conditions and treatment considerations.

    Main Methods:

    • Review of existing literature on Selective IgA deficiency.
    • Analysis of patient populations with increased incidence.
    • Discussion of the underlying B lymphocyte defect.

    Main Results:

    • Patients with IgA deficiency can produce diverse antibodies, including anti-IgA antibodies.

    Related Experiment Videos

  • The primary immunological defect involves the terminal differentiation of B lymphocytes.

    • Conclusions:

    • Treatment for Selective IgA deficiency should target the underlying associated diseases.
    • Patients require counseling regarding the risks of improperly administered blood products due to potential antibody responses.