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Updated: Oct 10, 2025

Habituation and Prepulse Inhibition of Acoustic Startle in Rodents
Published on: September 1, 2011
Response triggering by an acoustic stimulus increases with stimulus intensity and is best predicted by startle reflex
Dana Maslovat1, Christin M Sadler1, Victoria Smith1
1School of Human Kinetics, University of Ottawa, 125 University Private, Ottawa, ON, Canada.
Abstract:
In a simple reaction time task, the presentation of a startling acoustic stimulus has been shown to trigger the prepared response at short latency, known as the StartReact effect. However, it is unclear under what conditions it can be assumed that the loud stimulus results in response triggering. The purpose of the present study was to examine how auditory stimulus intensity and preparation level affect the probability of involuntary response triggering and the incidence of activation in the startle reflex indicator of sternocleidomastoid (SCM). In two reaction time experiments, participants were presented with an irrelevant auditory stimulus of varying intensities at various time points prior to the visual go-signal. Responses were independently categorized as responding to either the auditory or visual stimulus and those with or without SCM activation (i.e., SCM+/-). Both the incidence of response triggering and proportion of SCM+ trials increased with stimulus intensity and presentation closer to the go-signal. Data also showed that participants reacted to the auditory stimulus at a much higher rate on trials where the auditory stimulus elicited SCM activity versus those that did not, and a logistic regression analysis confirmed that SCM activation is a reliable predictor of response triggering for all conditions.
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