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Updated: Oct 10, 2025

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
Published on: August 4, 2011
Chronic myelogenous leukemia in a child following treatment for bilateral retinoblastoma
Haitham Hilal Al-Mahrouqi1, Anuradha Ganesh2, Abdulhakim Al-Rawas3
1Department of Ophthalmology, Ministry of Health, Al-Nahdha Hospital, Muscat, Sultanate of Oman.
Abstract:
A 3-year-old child was incidentally found to have chronic myelogenous leukemia (CML) during an admission for a routine ophthalmic examination under anesthesia. The child had received systemic chemotherapy and focal treatment for Groups C and D retinoblastoma in the right and left eye, respectively, when she was 7 months old. CML was treated with dasatinib, and the child attained a major molecular response. The child is now 3 years after treatment of CML, and the retinoblastoma remains inactive. CML following treatment of retinoblastoma is a rare occurrence. Long term and close monitoring of retinoblastoma patients who received systemic chemotherapy using serial blood tests is essential.
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