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Updated: Oct 10, 2025

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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
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Transoral Endoscopic Thyroidectomy by Vestibular Approach for Differentiated Thyroid Cancer Intraoperatively Invading
Xuan Hau Nguyen1,2, Xuan Hien Nguyen2, Thanh Long Nguyen1
1Department of Oncology, Hanoi Medical University.
Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
|December 9, 2021
Summary
Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is safe for T3b differentiated thyroid cancer invading strap muscles. This endoscopic total thyroidectomy and radioactive iodine therapy approach shows promising surgical and oncological outcomes.
Area of Science:
- Endocrine Surgery
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Transoral endoscopic thyroidectomy vestibular approach (TOETVA) is gaining popularity for thyroid cancer treatment.
- The efficacy of TOETVA for T3b stage thyroid cancer remains underexplored.
Purpose of the Study:
- To evaluate the surgical and early oncological safety and efficacy of TOETVA in patients with T3bN0M0 differentiated thyroid carcinoma.
Main Methods:
- A quasi-experimental study was conducted on 12 patients diagnosed with T3bN0M0 differentiated thyroid carcinoma.
- Patients underwent TOETVA between January 2019 and January 2021.
- Surgical outcomes and early oncological results were assessed.
Main Results:
- The mean operative time was 136.67 minutes with minimal blood loss (7.17 mL).
- No patients experienced transient hypoparathyroidism or nerve injuries (mental, recurrent laryngeal).
- All patients achieved undetectable thyroglobulin levels and normal neck ultrasounds post-radioactive iodine therapy.
Conclusions:
- TOETVA is a safe and effective surgical option for differentiated thyroid cancer with small tumors invading strap muscles.
- Endoscopic total thyroidectomy combined with postoperative radioactive iodine therapy provides good oncological control.
- Larger studies with longer follow-up are recommended to confirm these findings.

