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Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
Published on: November 1, 2018
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On track to tackle dengue: History and future of NS4B ligands
Mira A M Behnam1, Christian D Klein2
1Faculty of Pharmaceutical Engineering, The German International University, Cairo, Egypt.
Cell Host & Microbe
|December 9, 2021
Abstract:
A recent publication in Nature (Kaptein et al., 2021) reports a highly potent antiviral compound against dengue with promising efficacy in mice. Here, we track the history of this compound class, its pharmacology, and its chemistry, with insights into its potential as orally available drugs to prevent and treat dengue.

