Field-Effect Sensors Using Biomaterials for Chemical Sensing
Chunsheng Wu1, Ping Zhu1, Yage Liu1
1Institute of Medical Engineering, Department of Biophysics, School of Basic Medical Science, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
Sensors (Basel, Switzerland)
|December 10, 2021
Summary
This review explores advanced field-effect sensors utilizing biomaterials for chemical detection, inspired by natural olfactory and taste systems. These sensors offer high sensitivity for diverse applications, despite current challenges.
Area of Science:
- Biomaterials Science
- Chemical Sensing Technology
- Bio-inspired Engineering
Background:
- Biological chemical sensing systems (olfactory and taste) exhibit remarkable sensitivity and discrimination capabilities.
- Developing artificial field-effect sensors using biomaterials for high-sensitivity chemical detection presents significant challenges.
- Decades of research have yielded progress in biomaterial-based field-effect sensors for chemical sensing.
Purpose of the Study:
- To review recent advancements in field-effect sensors employing biomaterials for chemical sensing.
- To focus on sensors utilizing functional biomaterials like olfactory and taste cells/receptors as sensing elements.
- To introduce principles, sensor types, limitations, and future trends in this field.
Main Methods:
- Review of recent literature on biomaterial-based field-effect sensors.
- Categorization of sensors based on principles and sensing elements.
- Discussion of sensor types including Field-Effect Transistors (FET), Light-Addressable Potentiometric Sensors (LAPS), and Electrolyte-Insulator-Semiconductor (EIS) sensors.
Main Results:
- Significant progress has been made in developing field-effect sensors using biomaterials.
- Various sensor types (FET, LAPS, EIS) show promise for specific chemical detection.
- Functional biomaterials enhance sensor performance for detecting target chemicals.
Conclusions:
- Field-effect sensors using biomaterials demonstrate potential for high-performance chemical sensing.
- Continued research is needed to overcome current limitations and address challenges.
- Future trends point towards enhanced sensitivity and broader applications in biomedicine, environment, and food industries.


