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In Vitro Dissolution of Na-Ca-P-Oxynitrides
Natalia Anna Wójcik1,2, Polina Sinitsyna3, Sharafat Ali2
1Advanced Materials Center, Institute of Nanotechnology and Materials Engineering, Gdańsk University of Technology, 11/12 G. Narutowicza Street, 80-233 Gdańsk, Poland.
Abstract:
Sodium-calcium-phosphate based oxynitride glasses and glass-ceramics doped with Mg, Si, and Nb were studied in vitro in simulated body fluid (SBF) under static conditions. The release of ions and pH changes up to 7 days of immersion were investigated. The nitrogen incorporation into phosphate glass matrix was found to notably influence in vitro dissolution only of homogenous glasses. Increasing the nitrogen content in the samples decreased the mean mass loss, while the niobate incorporation increased it. The correlation between the nitrogen content and increase in pH of SBF was also observed. The presence of phosphates crystallites was found to support the dissolution process at the beginning step (up to 3 days).
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