[Relation between interleukin-2 production and the time of irradiation and mitogenic lymphocyte activation]

The effect of radiation on the production of interleukin 2 by activated lymphocytes was shown to be a function of time interval between irradiation and mitogen stimulation of cells. The most intensive production of interleukin 2 was noted in cells exposed 24 h following the effect of the mitogen. The enhancing effect of in vivo irradiation was less pronounced.