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Vulvar aphthous ulcer after COVID-19 vaccination
Sabrina Popatia1, Yvonne E Chiu1
1Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Pediatric Dermatology
|December 10, 2021
Summary
Vulvar aphthous ulcers, a rare condition causing genital sores, can occur after COVID-19 vaccination. This case highlights a potential immune response to the vaccine, distinct from infection-related ulcers.
Area of Science:
- Gynecology
- Immunology
- Infectious Diseases
Background:
- Vulvar aphthous ulcer (VAU), also known as Lipschutz ulcers, is an uncommon condition presenting as sudden vulvar ulcerations.
- It is typically non-sexually acquired and believed to be an immune response to infection or inflammation, often preceded by systemic symptoms like fever.
Observation:
- The COVID-19 pandemic saw reports of VAU associated with SARS-CoV-2 infection.
- This report details a case of VAU occurring subsequent to COVID-19 vaccination.
Findings:
- The presented case suggests that vulvar aphthous ulceration can be a rare adverse reaction to COVID-19 vaccination.
- This indicates a potential immunologic link between vaccination and VAU, similar to infection-related cases.
Implications:
- This finding expands the understanding of potential VAU triggers beyond infections.
- Clinicians should consider recent COVID-19 vaccination as a possible etiology for vulvar aphthous ulcers in young women.
- Further research is warranted to elucidate the precise immunologic mechanisms involved.
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