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Updated: Oct 10, 2025

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device
Published on: January 26, 2010
Modelling and simulation of occlusions in insulin pumps
Abstract:
An open source simulation model of the mechanical properties of a fully functional insulin pump was made in Matlab Simscape. The model simulates realistic behavior of an insulin pump, parts of which are validated against real-world systems. Simulations include mechanical forces and internal pressures, and the following fluid dynamics. Failure modes, such as occlusions, can be simulated and the resulting simulations can give new insights on how these failures affect the pump and how to detect them.Clinical relevance- Realistic pump simulations can be used to analyze how pump failures affect the system and in turn how to most effectively detect them before posing a hazard to the user, increasing the safety and reliability of the system.
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