Related Experiment Video

Updated: Oct 10, 2025

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
09:53

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

Published on: August 16, 2020

7.4K

An Ensemble Model for Tumor Type Identification and Cancer Origins Classification

Chenzhao Feng, Tianyu Xiang, Zixuan Yi

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 11, 2021
    PubMed

    Abstract:

    Tissue biopsy can be wildly used in cancer diagnosis. However, manually classifying the cancerous status of biopsies and tissue origin of tumors for cancerous ones requires skilled specialists and sophisticated equipment. As a result, a data-based model is urgently needed. In this paper, we propose a data-based ensemble model for tumor type identification and cancer origins classification. Our model is an ensemble model that combines different models based on mRNA groups which serve distinct functions. The experiment on the TCGA dataset exhibits a promising result on both tasks - 98% on tumor type identification and 96.1% on cancer origin classification. We also test our model on external validation datasets, which prove the robustness of our model.

    More Related Videos

    Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
    07:15

    Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

    Published on: August 16, 2020

    7.0K
    Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
    06:52

    Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres

    Published on: July 22, 2020

    6.7K

    Related Experiment Videos

    Last Updated: Oct 10, 2025

    Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography
    09:53

    Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography

    Published on: August 16, 2020

    7.4K
    Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
    07:15

    Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

    Published on: August 16, 2020

    7.0K
    Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
    06:52

    Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres

    Published on: July 22, 2020

    6.7K

    Related Concept Videos

    Mouse Models of Cancer Study02:43

    Mouse Models of Cancer Study

    5.8K
    Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
    The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
    5.8K
    Cancers Originate from Somatic Mutations in a Single Cell02:21

    Cancers Originate from Somatic Mutations in a Single Cell

    13.2K
    Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
    13.2K

    Articles linked to this work by shared authors, journal, and citation graph.

    Beyond Cause or Consequence: Intolerance of Uncertainty and Internalizing Symptoms in a Reciprocal Developmental Process During Adolescence.

    Journal of youth and adolescence·2026

    Phosphate Starvation Primes Plant Immunity through an ABA-OsbZIP12-Phytoalexin Signaling Network.

    Plant communications·2026

    Plant metabolites targeting mitochondrial dysfunction in cardiovascular diseases: pharmacological mechanisms and combination strategies.

    Frontiers in pharmacology·2026

    Invas: an inversion-aware method for transcriptome assembly.

    Nature communications·2026

    Engineered zwitterion-nanodelivery for precision targeting of brain metastases.

    Nature communications·2026

    Risk Assessment for Upper Urinary Tract Deterioration in Patients with Neurogenic Bladder: A Retrospective Study Using Interpretable Machine Learning Algorithms.

    International neurourology journal·2026

    Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    A Review of Exhaled Volatile Organic Compounds as Emerging Diagnostic Tools for Gastrointestinal Malignancies.

    Archives of Iranian medicine·2026

    Severe Macrocytic Anemia Uncovering Pernicious Anemia and Early-Stage Gastric Adenocarcinoma: A Case Report.

    Cureus·2026

    From Carcinoid Syndrome to Carcinoid Heart Disease: The Cost of Delayed Cardiac Surveillance.

    Cureus·2026

    Beyond VDR: Vitamin D Metabolism Genes in Tuberculosis Susceptibility, Immune Response and Implications for Diabetes Mellitus.

    Infection and drug resistance·2026

    Impact of Photodynamic Diagnosis on Immune Cell Infiltration in BCG-treated Non-muscle-invasive Bladder Cancer.

    European urology open science·2026

    LCN2 Associated With the Bidirectional Cardio-Kidney Link in Patients With Type 2 Diabetes and Cardiovascular-Kidney-Metabolic Syndrome.

    Medical science monitor : international medical journal of experimental and clinical research·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us