Investigation of Sleep-Dependent Activation-Interaction Association Network

The cortical activation and the interaction between cortical regions were considered to exist a strong correlation in recent neuroscience researches. However, such association during sleep was still unclear. The aim of the present work was to further investigate this association according to an activation-interaction association network. This study included 24 healthy individuals and all of them underwent overnight polysomnography. The absolute spectral powers of three frequency bands and the phase transfer entropy were extracted from six electroencephalogram channels. For each frequency band and sleep stage, activation-interaction association networks were built and correlation analysis was conducted by using Pearson correlation test. Results revealed the evident association between features derived from the two approaches during sleep, and as the sleep deepened, these correlation values attenuated in the alpha band, whereas the inversion happened in the delta band. This study exposed more detailed information of cortical activity during sleep, which will facilitate us to conduct research from a more comprehensive perspective, helping us make a more appropriate evaluation and explanation.