Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient disruption of bladder control linked to periaqueductal gray fibers following deep brain stimulation for psychiatric disorders.

Brain stimulation·2026
Same author

Real-Time Kinematic Adaptive Deep Brain Stimulation Safely Reduces Gait Impairment and Freezing of Gait in Parkinson's Disease.

medRxiv : the preprint server for health sciences·2026
Same author

HCN channels reveal conserved and divergent physiology in supragranular pyramidal neurons in primate species.

Communications biology·2026
Same author

Human Neocortical Glutamatergic Neurons Revealed Through Multimodal Profiling.

bioRxiv : the preprint server for biology·2026
Same author

Automated Monitoring and Clinical Notifications of Patient State for Neuropsychiatric Neuromodulation Studies.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Characterizing Deep Brain Stimulation Dual Device Beat Frequency Artifacts.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: Oct 10, 2025

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
10:46

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats

Published on: June 22, 2017

15.9K

Robustness of Beta Desynchronization from Chronically Implanted Cortical Electrodes on Multiple Time Scales.

Tomasz M Fraczek, Andrew L Ko, Howard J Chizeck

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 11, 2021
    PubMed
    Summary

    Adaptive deep brain stimulation (aDBS) using electrocorticography strips shows promise for essential tremor. Beta band biomarkers are reliable for long-term, implanted adaptive stimulation systems.

    More Related Videos

    Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
    07:52

    Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

    Published on: May 23, 2025

    410
    Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent
    08:31

    Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent

    Published on: November 30, 2017

    12.5K

    Related Experiment Videos

    Last Updated: Oct 10, 2025

    Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
    10:46

    Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats

    Published on: June 22, 2017

    15.9K
    Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
    07:52

    Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

    Published on: May 23, 2025

    410
    Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent
    08:31

    Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent

    Published on: November 30, 2017

    12.5K

    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Clinical Neurology

    Background:

    • Adaptive deep brain stimulation (aDBS) offers improved outcomes over conventional devices.
    • Fully implanted systems are crucial for clinical aDBS adoption.
    • Electrocorticography (ECoG) strips are investigated as a bio-marker source for adaptive stimulation control.

    Purpose of the Study:

    • To verify the long-term reliability of ECoG strips on the motor cortex for controlling aDBS.
    • To assess the robustness of beta band event-related desynchronization as a movement bio-marker for triggering aDBS.
    • To evaluate the feasibility of using ECoG strips in chronically implanted aDBS systems.

    Main Methods:

    • Utilized a unique longitudinal dataset from patients with essential tremor undergoing aDBS.
    • Recorded electrocorticography data from motor cortex strips over several months.
    • Analyzed beta band event-related desynchronization as a bio-marker for adaptive stimulation control.

    Main Results:

    • Beta band event-related desynchronization proved robust as a bio-marker for triggering aDBS.
    • A minor increase in beta band event-related desynchronization was observed over several months with active aDBS.
    • Confirmed the potential for ECoG strips in chronically implanted systems.

    Conclusions:

    • Cortical ECoG strips are a promising and practical bio-marker source for fully implanted, clinically translatable aDBS systems.
    • The reliability of beta band desynchronization supports its use in long-term adaptive stimulation for movement disorders.
    • This study highlights the feasibility of advanced aDBS for improved patient care.