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[The Biological Significance of Platelet Polar Movement-Review]

Xin Zhang1, Xiao-Jun Yuan2, Mo Yang3

  • 1Department of Pediatric Hematology and Oncology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China.

Zhongguo Shi Yan Xue Ye Xue Za Zhi
|December 11, 2021
PubMed

Platelets are key participants in many pathophysiological processes, play a broad role in tissue regeneration and repair, and interact closely with tumor cells. Platelets have active and passive migration in the human body, and they play different biological meanings, including antimicrobial host defense, inflammation, autoimmune response, tumor growth and metastasis, etc. Therefore, in-depth understanding of the structure and function of platelets, and targeted platelets as biomarkers have become particularly important in the field of modern medical research and treatment. This review provides an overview of platelet physiology, focusing on the biological characteristics of platelet polarity movement and its significance in diseases.

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